Lionel and Jenny after wonderful news, Jenny is pregnant, but they only share the news with Tom and Helen, reason being Lionel doesn't want George making jokes about what color the baby will be. However, when Florence overhears the news she accidentally lets slip to Louise and she in turn tells George which leads to yet another argument.
George is ecstatic when he learns he's been named Small Businessman of the Year. However, Louise quickly learns that the basis of the award is purely physical. The award is to honor short businessmen.
Louise is excited when she receives a letter from her old boyfriend, Bill Simpson, asking her out to dinner. However, she decides not to go because she knows George will be upset if she does, so Florence secretly goes and pretends to be Louise, but things get really confusing for Bill when Louise changes her mind and shows up with George in tow.
It's Halloween, and the Jeffersons and the Willis are all gearing up for a costume contest, they're each going as old movie stars. Meanwhile, Harry brings his telescope over onto the Jefferson's balcony to view a specific star, this leads to Louise taking a peek but what she sees is totally unexpected, she sees someone dressed as a rabbit murder someone.
When the Killer Rabbit overhears Louise telling Harry what she saw through the telescope, he follows her to her apartment and waits until everyone leaves to confront her. The Killer Rabbit soon finds that killing Louise is not going to be an easy task with constant interruptions preventing him.
While going through a bunch of old items, George and Louise discover an old will which belonged to his father. The will states that his father wanted to be buried next to Mother Jefferson, so George sets out to do just that but quickly discovers that this is no easy task.
Lionel becomes overwhelmed with advice on being a father when he and Jenny arrive at the Jefferson apartment, one evening which prompts him to storm out.
George takes Marcus to the gym to teach him how to box, after the boyfriend of a girl that Marcus made a move on beats him up. However, George's bigmouth gets him in the ring with another boxer but George is confident he'll win since he used to be called ""Joltin' George.""
With all the excitement over Jenny's pregnancy, Florence begins to hear her biological clock ticking. This prompts her to find a prospective husband and father through a dating service.
Louise is to present a Volunteer award and must take care of the engraving on the plaque. However, when Florence takes it to her cousin, he mispells the name. This leads to a huge fight between Florence and Louise which results in Louise firing her. When George hires her back to serve some guests he's entertaining, constant bickering erupts.
Louise is excited when she gets to have an orphan, stay at the Jefferson's apartment for a week. However, when she and Florence go out to the store and leave George in charge some of his prejudiced attitudes rub off on the impressionable young lady leading to what was supposed to be a week turns into only a few hours.
While making a dry cleaning delivery at a mental institution, George is accidentally mistaken as a mental patient, when the real patient escapes disguised as George.
Louise is ecstatic when she learns that a television documentary will be done on the suicide helpline available down at the Help Center, and she is going to be interviewed. However, in the midst of all the excitement, Louise inadvertently neglects a teenage girl who later swallows a bottle of pills.
When two old friends of Helen's come for a visit, Tom feels like a ""white"" outsider in his own home. This prompts him to ask George to teach him how to act black.
George and Louise are disappointed with the news that if Lionel gets the job that he's getting interviewed for, Jenny and him will have to move to Boston. Meanwhile, when Tom comes down with the flu, he can't take Jenny to her Lamaze class which prompts George to take her, but when the class is over and everyone has gone, George gets stuck there with Jenny, who has gone into labor.
George rushes Jenny to the hospital as she begins having contractions. Meanwhile, Lionel is offered the job in Boston, and returns from the interview to find out the news the Jenny has gone into labor. At the hospital, the family gathers and George begins to worry if the baby's skin color will be black or white.
George and Louise are happily planning a belated baby shower for Jenny and Lionel. However, as soon as the shower begins, a workaholic Lionel walks out, leaving behind a lonely wife.
When Louise, Helen, Florence and Jenny go out for the day, George, Tom and Lionel are left to take care of baby Jessica. They soon find out that taking care of a baby is no easy chore and the Jefferson apartment begins to slowly turn to shambles.
Louise is planning a surprise party for George's 50th birthday and has invited all his friends to meet up at the Willis for the party. Meanwhile, George gets the idea to throw a birthday party for himself and finds all his friends refusing to attend this leads him to wallow in Charlie's bar.
On their anniversary, George and Louise get into an argument over his honesty, this prompts George to storm out to a hotel and Louise is left to think about George's fidelity. Things get worse when she arrives at his hotel and discovers a young woman in his room.
Lionel and Jenny are excited with the news that they're trying to purchase a home. However, when the bank turns down their loan application, George, Louise, Helen and Tom each go down to the bank to help them get one, after each promising not to interfere.
George is excited when he learns he will be able to expand his store on the first floor of the building. However, his excitement starts to dwindle when he learns the expansion means taking over Charlie's bar, since Charlie's lease is not being renewed.
As Louise and George look through old photos, they recall George opening his first store in 1968. His opening coincides with the assassination of Martin Luther King, Jr and when news of his death circulates, chaos erupts in the Jeffersons' neighborhood.
While babysitting his granddaughter, Jessica, George entertains her with his version of King Arthur, King George. In his tale, King George is defending his kingdom from the evil, Inflation.